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Determination of vitamin E levels was carried out on purified extract samples and on each formula. Emulgel was then evaluated for physical characteristics (pH, viscosity, adhesion, dispersion and stability). The results of the purified extract were then formulated into emulgel with three concentrations of 3% (F1), 6% (F2) and 9% (F3). The study was started from the extraction using maceration method with petroleum ether solvent, followed by extract purification using column chromatography with n-hexane solvent. This study aimed to determine the levels of vitamin E in extracts after purification, physical property test of emulgel with variations in extract concentration and vitamin E levels in emulsions. The formulation of purified Moringa leaf extract is needed so that the vitamin E content in it is more maximal.
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MENKES/PER/2010 tentang saintifikasi jamu dalam penelitian berbasis pelayanan kesehatan. MENKES RI, 2010, Peraturan Menteri Kesehatan Republik Indonesia Nomor 003. Kumar, S., Pandey, AK., 2013, Chemistry and biological activities of flavonoids: an overview, The Scientific World Journal, 2013: 1-15 Krisyanella, K., Susilawati, N., Rivai, H., 2017, Pembuatan Dan Karakterisasi Serta Penentuan Kadar Flavonoid Dari Ekstrak Kering Herba Meniran (Phyllanthus niruri L.), Jurnal Farmasi Higea. Jayani, NIE., Kartini., Putri, LK., 2020, Standardization of a Crude Drug Moringa oleifera Leaf from Africa, India and Local (Indonesian) which Cultivated in Bojonegoro Indonesia, International Journal of Pharmaceutical Research. Departemen Kesehatan Republik Indonesia, Jakarta Departemen Kesehatan Republik Indonesia, JakartaĭEPKES RI, 2000, Parameter standar umum ekstrak tumbuhan obat. and their pharmacological properties: a review, Journal of Pharmacy and Pharmacology. 53(0):6-15.īagalkotkar, G., Sagineedu, S., Saad, M., Stanslas, J., 2006, Phytochemicals from Phyllanthus niruri Linn. The results showed that Phyllanthus niruri and Sonchus arvensis from the three places did not meet the standard requirement.Īmessis-Ouchemoukh, N., Madani, K., Falé, PLV., Serralheiro, ML., Araújo, MEM., 2014, Antioxidant capacity and phenolic contents of some Mediterranean medicinal plants and their potential role in the inhibition of cyclooxygenase-1 and acetylcholinesterase activities, Industrial Crops and Products.
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The methods of the determination referred to the Indonesian Herbal Pharmacopoeia 1 st Edition (2008).
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This study was aimed to determine the specific parameters (macroscopic, microscopic, total flavonoid content, water-soluble extract content, and ethanol-soluble extract content) and non-specific parameters (loss on drying, total ash content, and acid insoluble ash content) of Phyllanth us niruri and Sonch us arvensis collected from Batu, Tawangmangu, and Bogor. Components of the Scientific Jamu are standardized to ensure that these materials meet the predefined quality. Phyllanthus niruri and Sonchus arvensis are two of the 30 medicinal plants processed into Scientific Jamu. Jamu has been empirically explored as a composition of various crude drugs, hence called as Scientific Jamu. Saintifikasi Jamu, or the scientific investigation of Jamu, is an evidence-based process to ensure the safety and efficacy of herbal medicine through health service research.